EB0002 Research Methodology Matrix Sample

Full citation of selected article Article #1 Article #2 Article #3 Article #4
Punab, M., Poolamets, O., Paju, P., Vihljajev, V., Pomm, K., Ladva, R., Korrovits, P. & Laan, M. (2017). Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts. Human Reproduction, 32(1), 18-31. doi:10.1093/humrep/dew284 Deshpande, P. S., & Gupta, A. S. (2019). Causes and Prevalence of Factors Causing Infertility in a Public Health Facility. Journal Of Human Reproductive Sciences, 12(4), 287–293. https://doi.org/10.4103/jhrs.JHRS_140_18 Moramazi, F., Roohipoor, M., & Najafian, M. (2018). Association between internal cervical os stenosis and other female infertility risk factors. Middle East Fertility Society Journal, 23(4), 297-299. doi:10.1016/j.mefs.2018.02.002 He, Y., Tian, J., Oddy, W. H., Dwyer, T. & Venn, A. J. (2018). Association of childhood obesity with female infertility in adulthood: a 25-year follow-up study. Fertility and Sterility, 110(4), 596–604.e1. doi:10.1016/j.fertnstert.2018.05.011
Why you chose this article and/or how it relates to the clinical issue of interest (include a brief explanation of the ethics of research related to your clinical issue of interest)  

I chose this article because it highlights the causes of severe infertility in men. From this study, I found out the reasons behind heterogeneous male infertility and how personalized treatment can be utilized to treat the condition.

This article lists major findings related to marital decline in Europe.

Concerning the ethics of research, I find that the authors did not fabricate or falsify data but reported accurately their observations from the experiment.

I chose this article because it helps me to understand the trend in the causes of infertility in the contemporary population. The study examines how infertility changes with local demographics. This article relates to my issue of clinical interests since it tracks the trend of infertility by looking at the leading causes of infertility in modern times.  

Concerning ethics of research, this article was objective in that it avoided bias and strictly observed the clinical guidelines followed in a research such as correct data analysis and interpretation.

I chose this article because it gives a critical perspective of how cervical factor has led to infertility in women

My reason for choosing this article is because it looks at how women become victims of infertility courtesy of cervical stenosis. Concerning ethics of research, this article adhered to the principles of objectivity, honesty, integrity, and accurate reporting.  

I chose this article because it helps me to understand whether there is any relationship between childhood obesity and infertility. This article examines whether those who had obesity when they were young have a higher probability of being infertile. Concerning ethics of research, this article adhered to the principle of accurate reporting. Furthermore, the authors clearly stated what they were able to achieve and what they did not regarding infertility in their experiment.


Brief description of the aims of the research of each peer-reviewed article The objective of this study was to find out the causes of severe infertility in men. The authors wanted to find out the causal factors for male infertility and what causes impaired spermatogenesis. The objective of this study was to find out the reasons why young women and men are increasingly becoming childless. In addition, the authors sought to calculate the proportion of individual factors that contribute to infertility in a population of patients presenting in a local healthcare facility. The study established that primary infertility was responsible for 57.5% of the cases, while secondary infertility accounted for 42.5% of the cases. The objective of this work is to examine the infertility risk factors in women. Specifically, the study sought to examine why cervical os stenosis has become one of the leading risk factors for infertility in women. The aim of this article is to find out if there is any relationship between childhood obesity and infertility in women. The researchers wanted to find out why young girls aged 7 and 11 with a higher BMI index were at a higher risk of becoming infertile when they reach reproductive age.
Brief description of the research methodology used Be sure to identify if the methodology used was qualitative, quantitative, or a mixed-methods approach. Be specific.  

The authors utilized a prospective clinical-epidemiological design in analyzing male factor infertility. The study was a mixed method research since it used both qualitative and quantitative data to conduct the inquiry. An epidemiology study was performed to study how infertility occur among different groups of men.

This study was a cross-sectional observational study conducted in an infertility clinic, hence quantitative. The researchers examined 120 couples with a view of establishing the respective causes of infertility and evaluating the respective prevalence. This study was an analytical cross-sectional study that recruited 168 infertile women. The researchers further divided the study population into two groups. The first comprised of those with cervical stenosis (n=84) and the second, which was the control group, comprised of those without cervical stenosis (n=84). This study is purely a quantitative study since it examined the correlation between internal cervical os stenosis and other factors responsible for female infertility.   This was a Prospective longitudinal study. This was purely a qualitative study aimed at finding out why young girls between the ages of 7-11 who had experienced childhood obesity have a high propensity to become infertile compared to girls who never had childhood obesity


A brief description of the strengths of each of the research methodologies used, including reliability and validity of how the methodology was applied in each of the peer-reviewed articles you selected. The strength of the study draws from the fact that it comprehensively analyzes the causative, absolute and plausible factors responsible for male infertility. Further, the study findings are reliable since the researchers examined a large sample of patients (1737) over a long period (2005-2013).

Finally, the authors are professionals in the field of study, an aspect that further reinforces the reliability of the study.

The strength of this study relates to the fact that it recruits and examines individuals presenting to an infertility clinic for treatment, hence utilizes primary data in understanding the causes and the respective prevalence of the causes within the population under study. The method adopted for the study is both reliable and valid as it involves observing the population’s presentation with minimal interference.  

By examining the correlation between cervical os stenosis and other infertility causative factors, the authors have successfully provided a better way of managing female infertility that is associate with cervical stenosis. This ultimately defines the strength of the study.


External validity can be increased by using broad inclusion criteria that result in a study population that more closely resembles real-life patients, something that the authors have done particularly well.

Secondly, the study findings of this study have exceptional validity since the authors sought to study population trends.

General Notes/Comments